Research

Title: Comparative Analysis of Rapid Immunochromatography test & ELISA in the detection of Leptospirosis, Department of Microbiology (2011).

Sponsoring agency SD Diagnostics

Dr K L Ravikumar, Prof & HOD Department of Microbiology

Year in which started 2011

Duration in months 6 months

Research Objectives

To compare the sensitivity and specificity of point of care test(POCT) and ELISA for the diagnosis of Leptospirosis infection in hospital setup.

Research outcomes

  • Leptospirosis is a re-emerging infectious disease that is under-recognized.
  • In the present investigation the serological specificity of leptospiral lipopolysaccharides (LPS) was evaluated by enzyme linked immunosorbent assay (ELISA) and rapid immunochromatography based lateral flow assay.
  • Sera samples from 110 cases with febrile illness were evaluated for the diagnostic sensitivity and specificity.
  • The LFA showed sensitivity of 92% and specificity of 90% in comparison with ELISA.

Title: Laboratory Diagnosis Malaria by Peripheral Smear, QBC, Antibody detection (Biolard) & Antigen Antibody detection(SD Diagnostics) & Microarray(SD Diagnostics) Microbiology (2011).

Sponsoring agency SD Diagnostics

Dr K L Ravikumar, Prof & HOD Department of Microbiology

Year in which started 2011

Duration in months 6 months

Research Objectives

To evaluate the conventional tests with Microarray for diagnosis of Malaria.

Research outcomes

In the study Peripheral smear, QBC and Antibody detection, Antigen Antibody detection and Microarray showed the sensitivity of 87%,94%,94%,96% and 99% respectively. Microarray showed the highest sensitivity in comparison with other tests.